POEMS Syndrome Diagnosed 10 Years after Disabling Peripheral Neuropathy

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POEMS Syndrome Diagnosed 10 Years after Disabling Peripheral Neuropathy

Peripheral neuropathy is characterized as a generalized, relatively homogeneous process affecting many peripheral nerves and predominantly affecting distal nerves. The epidemiology of peripheral neuropathy is limited since the disease presents with varying etiology, pathology, and severity. Toxic, inflammatory, hereditary, and infectious factors can cause damage to the peripheral nerves resulti...

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POEMS syndrome is a unique clinical entity, the diagnosis of which is made when polyneuropathy and monoclonal gammopathy occur together, associated with other changes such as organomegaly, endocrinopathy, skin changes and papilledema. Cutaneous manifestations are heterogeneous, with diffuse cutaneous hyperpigmentation, hemangiomas and hypertrichosis occurring more frequently. We report the case...

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The idiopathic hypereosinophilic syndrome (HES) represents a leukoproliferative disorder, characterized by unexplained prolonged eosinophilia (>6 months) and evidence of specific organ damage. So far, the peripheral neuropathy associated with skin manifestations of HES has not been reported in the dermatologic literature although the incidence of peripheral neuropathy after HES ranges from 6~52...

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Peripheral neuropathy in Cockayne's syndrome.

Moosa, A., and Dubowitz, V. (1970). Archives of Disease in Childhood, 45, 674. Peripheral neuropathy in Cockayne's syndrome. A detailed study has been made of a typical case of Cockayne's syndrome. An associated peripheral neuropathy has been demonstrated by slow nerve conduction velocities and by evidence of segmental demyelination on sural nerve biopsy. Cockayne's syndrome is probably a leuco...

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ژورنال

عنوان ژورنال: Case Reports in Medicine

سال: 2011

ISSN: 1687-9627,1687-9635

DOI: 10.1155/2011/126209